After flying around in space, when I open the "m" screen I can see my mouse cursor somewhere in the main body of the screen, but the first time I move my mouse the cursor pops to the top left of the screen. After that I can move my mouse around normally.

After I close the screen, the first time I move my mouse around in space my ship spins around. I can only assume it has something to do with the same mouse bug I've been encountering. If I don't move my mouse and open the "m" screen, my mouse appears in the middle of the screen, and doesn't bug out when I move it the first time. The same goes with closing the "m" screen -- if I never moved my mouse in the screen, then my ship won't spin out if I close the screen.

I have pretty much all of the settings set to low, but it happened the first time I tried playing on the default settings.

It's pretty annoying :D

MacBook Pro (Retina, 15-inch, Early 2013)
2.4 GHz Intel Core i7
8 GB 1600 MHz DDR3
NVIDIA GeForce GT 650M 1024 MB
Intel HD Graphics 4000 1536 MB

This behaviour started after the VO 1.8.430 update.

Fixed in Update 1.8.433 that was just released.