Is there anyway to switch from full screen VO to the Desktop?

Yes. At least, I think so. Let mee see...

Options>video>fullscreen/windowed

command tab brings up a neat little list of things you can switch betweetn

Command tab only works if you're already in windowed mode.

ATTENTION DEVS AND PEOPLE:
THIS IS A SUGGESTION

Certain apps, like SAFlashPlayer, on Mac, and a few others, run "Fullscreen" mode as a large window with no top-bar, and remove the Finder bar on top. Or something like that. This puts it into "Fullscreen" while you can still switch to things, minimize, etc. Could this be done with VO?

No.

why?

Because it could be very damnde handy.

or...the devs could make a handy little keyboard command to enable swithcing between windowed and full screen :)

Of course it will adjust the resolution in the process

I totally agree
I was looking for a while (when I started) for the Command-Key that would switch from Fullscreen to Windowed.
Sorry, but pressing escape and messing with the Video settings, just isn't what I had in mind.
It's gotta work like Command-Tab (switch apps to Mail, Firefox, whatever)

Now, if I had that, I wouldn't mind updating www.vo-wiki.com from time to time when doing slow things like trading or mining.

-- Foo Fighter